The FDA is said to have of late instituted a crack down on weight loss supplements as a result of severe side effects and even death associated with some dietary supplements like ephedra. The ban on ephedra products resulted to the development of so-called ephedra free weight loss supplements, these too are said to yield their fair share of conditions and they too could possibly be destined to the same fate as ephedra.

These ephedra free medications are said to cause a rise in heartbeat and a few other unintended effects on healthy men and women based on a health expert who participated in the research project.

The study carried out with the University of California at Berkeley was the primary one to go into the health effects of reformulated weight loss supplements. On the list of things screened for included blood pressure and heart beat rate of volunteers who were given reformulated weight loss supplements made from extracts of bitter orange.

Ever since the ban slapped on ephedra by FDA, an ever-increasing figure of unwanted weight loss product manufactures have changed to extracts of bitter orange. The USB examination involved 20 healthy volunteers, who were given sole doses of a weight loss supplement or a placebo.

The diet supplements tested in the research were Xenadrine EFX and Advantra Z, each of which incorporates bitter orange extracts. The managed drug was shown to produce a slight increase in cardio pulse rate of up to 16 beats in one minute. The Thermogenic Xenadrine EFX in particular was shown to rev up heartbeat by 13 per cent, something that makes it almost identical in performance to ephedra.

Bitter orange extracts include synephrine, a part specific to over 90% of citrus fruits but found in increased concentrations in fruits such as Sour orange, Zhi shi and bitter orange and that is popularly used as a medication in the control of respiratory tract congestion and blood pressure. Xenadrine EFX features a stimulant in the part, usually caffeine. The amount of caffeine is Xenadrine is thought to be roughly the same as 3 coffee cups. This is the ingredient responsible for the increase in blood pressure and people using this product are cautioned against over dosage.

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